Relationship between monocyte-HDL ratio and disease process and pulmonary functions and pulmonary hypertension in stable COPD patients

Purpose: Inflammation is a major factor in the pathophysiology of chronic obstructive pulmonary disease (COPD), and molecules implicated inflammation include monocytes high-density lipoprotein-cholesterol (HDL-C). The primary goal study was to look at relationship between function hypertension (PH) COPD monocyte HDL ratio (MHR).
 Materials Methodsː conducted by acquiring retrospective data from previously recorded questionnaires hospital databases for 239 individuals over age 40 with diagnosis who admitted outpatient clinic. Patients whose were missing not included analysis. Two groups patients created: those high MHO levels without. Analysis done on correlation tests. presence PH analyzed second stage. 
 Resultsː median 62.22 ± 9.37 year 88.7% them male. With exception smoking, there no statistically significant link MHR analyses, however negative connection post-bronchodilation (post-BD) FEV1/FVC MHR. Additionally, association found absolute value RV/TLC. However, older (OR=0.949, 95% CI (0.915, 0.984)), having more than three comorbidities (OR=2.174, (1.045, 4.521)), body mass index (BMI) below 25 have all been linked an increased risk patients.
 Conclusionː Although conclusively established, it functions. that presented also came conclusion may be significantly advanced age, numerous comorbidities, low weight. These problems must investigated validated larger, multicenter patient populations.